Yes! Ever since the rumoured spoilers were released I've been wondering if Yuuko healed Watenuki using the vampire blood she had previously gotten from the twins for their payment to travel dimensions, lol.
Lets see... (various CLAMP spoilers ahead)
Wish - It took Kohaku being forced to return to Heaven before he and Shuichiro realized their love for each other. No near death experience but they both were under the impression they would never see each other again since Kohaku wouldn't be allowed to return to Earth, which is probably worst.
CCS - Yukito got hurt before Touya and him got together.
MKR - Eagle almost dies before he and Lantis start to realize their feelings. Although they never admit it to each other by the end of the story, you have the main character, Hikaru, trying to set them up because she knows, so I'm counting it.
Tokyo Babylon - it took Seishirou getting hurt for Subaru to admit his love.
X - Kamui's feelings for Fuuma are not clear until after Fuuma joins the Dragons of Earth, which resulted in a huge injury towards Kamui which he wouldn't have recovered from if it wasn't for Subaru and it the start of Fuuma molesting Kamui ever chance he got.
Legal Drug - Kazahaya would have died a couple of times now if it wasn't for Rikuo.
RG Veda - it takes Ashura going into his God of Destruction mode before Yasha realizes he loves him more than as father/son, which almost resulted in his own death but Ashura stabs himself instead.